Bronopol BP, Bronopolum
Bronopol (2-Bromo-2-nitro-1,3-propanediol) BP, Bronopolum
Bronopol (2-Bromo-2-nitro-1,3-propanediol) BP is an organic compound which is used as an antimicrobial. It is a white solid with purity 99% min. Bronopol BP grade is made by the bromination of di(hydroxymethyl)nitromethane, which is derived from nitromethane by a nitroaldol reaction.
Properties:
BNP pure product is white to powder or crystal, odorless and tasteless, melting point 118°C, its solubility (25°C): water 25g/100g, oil 0.5g/100g, oil/water partition coefficient is small. Its aqueous solution decomposes slowly when alkaline, and cannot be used with certain metals (such as aluminum). It is unstable under high temperature and alkaline conditions and turns brown under light.
Solubility:
Bronopol powder is readily soluble in water; the dissolution process is endothermic. Solutions containing up to 28% w/v are possible at ambient temperature. It is poorly soluble in non-polar solvents but shows a high affinity for polar organic solvents.
Usage and applications:
Bronopol (2-Bromo-2-nitro-1,3-propanediol) BP is used in consumer products as an effective preservative agent, as well as a wide variety of industrial applications (almost any industrial water system is a potential environment for bacterial growth, leading to slime and corrosion problems - in many of these systems Bronopol can be a highly effective treatment).
Mainly used in industrial circulating water, paper pulp, coatings, plastics, cosmetics, wood, cooling water circulation systems, and industrial use of sterilization, anti-mildew, anti-corrosion, and algae killing.
The use of bronopol in personal care products (cosmetics, toiletries) has declined since the late 1980s due to the potential formation of nitrosamines. While Bronopol BP is not in itself a nitrosating agent, under conditions where it decomposes (alkaline solution and/or elevated temperatures) it can liberate nitrite and low levels of formaldehyde and these decomposition products can react with any contaminant secondary amines or amides in a personal care formulation to produce significant levels of nitrosamines (due to the toxicity of these substances, the term 'significant' means levels as low as 10s of parts per billion).
Manufacturers of personal care products are therefore instructed by regulatory authorities to 'avoid the formation of nitrosamines' which might mean removing amines or amides from the formulation, removing Bronopol from a formulation, or using nitrosamine inhibitors.
Our factory professcial produce Bronopol with BP Standard. Free sample could be supplied for customers testng. If you have interest, pls contact us freely. Appreciate your contact.
